Well, since you're expert and l33t RPG makers it shouldn't be too difficult for any of you to do this
And to walk right is no problem. Just make sure that the UP key makes the character walk up/right or up/left. There's plenty of games that implement this nicely even though the only I can come up with right now in the middle of the night is tactics games like FF Tactics, Tactics Ogre and Fallout for that matter, even though that uses some kind of heaxagonical system (Did just make up a term?
) and mouse point and click to move. The only difficulty I see (if you're a person who know how to write scripts and such) is to actually make all of the tile sets. Personally, with my level of experience of this, I wouldn't get into that in standard 2d and definitely not in isometric.