I never played system shock though I've looked at it several times in the steam store. I loved Deus Ex: Human Revolution because it combined robotics, stealth, and firefights into an RPG feeling game and the story is actually one that has you captivated for the full ride. Bioshock isn't quite the same, it's great and I loved all three but I wouldn't put it in the same genre. Though they are both sci-fi, one has a historic feel while the other futuristic. Perhaps it's my interest in future technologies that drives me to say so.