Okay so here's something that I hope hasn't been tried yet or at least not for a while.Think of a video game character and a good actor or actress that would play that character well in a movie.
(Note) You can't use actors in movies based off of video games but you can re cast a game that has been made into a movie in the past.
There are endless possibilites just make sure you have a reaosn for why you chose that actor/actress.
I'l start this off
Dante, from Devil May Cry. I picked actor James Marsters (he played Spike in Buffy the Vampire Slayer). James has a similar attitude to Dante's. James also has that "badass" demenor to him that I think goes well with Dante's personality.